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  • 产品名称：PuromycinDihydrochloride

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  • 产品厂商：Biovision
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简单介绍：
PuromycinDihydrochloride
详情介绍：
Characteristics A nucleoside antibiotic. It inhibits protein synthesis by disrupting peptide transfer on ribosomes causing premature chain termination during translation. It is a potent translational inhibitor in both prokaryotic and eukaryotic cells. Resistance to puromycin is conferred by the puromycin N-acetyl-transferase gene (pac) from Streptomyces. Puromycin has a fast mode of action, causing rapid cell death at low antibiotic concentrations. Adherent mammalian cells are sensitive to concentrations of 2 to 5 µg/mL, while cells in suspension are sensitive to concentrations as low as 0.5 to 2 µg/mL.
Purity ≥ 98 % by HPLC
Chemical Name 3'-[α-Amino-p-methoxyhydrocinnamamido]-3'-deoxy-N,N-dimethyladenosine dihydrochloride
Formula C₂₂H₂₉N₇O₅ • 2HCl
Permeability Not-permeable
Molecular Weight 544.43 g/mol
CAS-No 58-58-2
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
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image for Puromycin Dihydrochloride (ABIN629203) Puromycin Dihydrochloride