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  • 产品名称：ABT-888

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  • 产品厂商：Biovision
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简单介绍：
ABT-888
详情介绍：
Characteristics Potent inhibitor of PARP-1 and PARP-2 (potency ≤5 nM in vitro). Does not inhibit other NAD-binding enzymes. Has minimal CYP450 inhibition and induction. Shows broad spectrum of chemo- and radio-potentiation. Does not show inherent cytotoxicity and shows no single agent activity in tumor models.
Purity ≥ 98 % by HPLC
Chemical Name 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide . dihydrochloride
Formula C₁₃H₁₆N₄O.2HCl
Permeability Cell-permeable
Molecular Weight 317.21 g/mol
CAS-No 912445-05-7
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
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image for ABT-888 (ABIN412223) ABT-888