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  • 产品名称：GDC-0941

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  • 产品厂商：Biovision
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简单介绍：
GDC-0941
详情介绍：
Characteristics GDC-0941 is a potent inhibitor of p110alpha and p110delta (IC50 = 3 nM). It selectively binds to PI3K isoforms in an ATP-competitive manner, inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K/Akt signaling pathway.
Purity ≥ 99 % by HPLC
Chemical Name 2-(1H-Indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)-thieno[3,2- d]pyrimidine
Formula C₂₃H₂₇N₇O₃S₂
Permeability Cell-permeable
Molecular Weight 513.64 g/mol
CAS-No 957054-30-7
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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image for GDC-0941 (ABIN412227) GDC-0941