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  • 产品名称:Apicidin

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简单介绍:
Apicidin
详情介绍:
Characteristics A potent, cell permeable inhibitor of histone deacetylase (IC50 = 700 pM for parasitic histone deacetylase). Inhibits HeLa cell proliferation (IC50 = 50 - 100 nM) and induces the transcriptional activation of p21 (WAF1) in a reversible manner. Also prevents H-ras-induced invasive phenotype of MCF-10A cells possibly by down regulating MMP-2 in a reversible manner.
Purity ≥ 95 % by HPLC
Chemical Name cyclo-L-(2-Amino-8-oxodecanoyl)-L-(N-methoxy-tryptophan)-L-isoleucyl-D-pipecolinyl]Suberoylanilide hydroxamic acid
Formula C₃₄H₄₉N₅O₆
Permeability Cell-permeable
Molecular Weight 623.8 g/mol
CAS-No 183506-66-3
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
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