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  • 产品名称：XAV939

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  • 产品厂商：Biovision
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简单介绍：
XAV939
详情介绍：
Characteristics A Tankyrase (TNKS) inhibitor (IC50 = 110 nM for TNKS1 and 4 nM for TNKS2). Antagonizes wnt signaling via stimulation of beta-catenin degradation and stabilization of axin. Inhibits proliferation of the µ-catenin-dependent colon carcinoma cell line DLD-1.
Purity ≥ 98 % by HPLC
Chemical Name 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thi opyrano[4,3-d]pyrimidin-4-one
Formula C₁₄H₁₁F₃N₂OS
Permeability Cell-permeable
Molecular Weight 312.31 g/mol
CAS-No 284028-89-3
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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image for XAV939 (ABIN412327) XAV939