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  • 产品名称：A83-01

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  • 产品厂商：Biovision
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简单介绍：
A83-01
详情介绍：
Characteristics A selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-beta-induced epithelial-to-mesenchymal transition. Helps maintain homogeneity and long-term in vitro self-renewal of human induced pluripotent stem cells (iPSCs).
Purity ≥ 98 % by HPLC
Chemical Name 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-p yrazole-1-carbothioamide
Formula C₂₅H₁₉N₅S
Permeability Cell-permeable
Molecular Weight 421.52 g/mol
CAS-No 909910-43-6
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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image for A 83-01 (ABIN412325) A 83-01