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  • 产品名称：PAC-1

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  • 产品厂商：Biovision
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简单介绍：
PAC-1
详情介绍：
Characteristics Procaspase-activating compound 1 (PAC-1) directly activates procaspase-3 to caspase-3, a transformation that allows induction of apoptosis even in cells that have defective apoptotic machinery. In cancer cells, PAC-1 had an IC50 value of 3 nM for induction of cell death, whereas in cells from adjacent normal tissue had IC50 values of 3.2-8.5 µM.
Purity ≥ 95 % by HPLC
Chemical Name 2-[[2-Hydroxy-3-(2-propen-1-yl)phenyl]methylene]hydrazide 4-(phenylmethyl)-1-piperazineacetic acid
Formula C₂₃H₂₈N₄O₂
Permeability Cell-permeable
Molecular Weight 392.49 g/mol
CAS-No 315183-21-2
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage 4 °C
Expiry Date 24 months
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image for PAC-1 (ABIN412254) PAC-1