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  • 产品名称：SB-431542

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  • 产品厂商：Biovision
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简单介绍：
SB-431542
详情介绍：
Characteristics A potent and selective inhibitor of the TGF-beta1 receptor ALK5 (IC50 = 94 nM). It inhibits ALK4 only at higher concentrations (IC50 = 140 nM). Suppresses renewal in embryonic and induced pluripotent stem (iPS) cells and promotes their differentiation through its effect on Smad signaling pathway.
Purity ≥ 98 % by HPLC
Chemical Name 4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide
Formula C₂₂H₁₈N₄O₃
Permeability Cell-permeable
Molecular Weight 384.39 g/mol
CAS-No 301836-41-9
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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image for SB-431542 (ABIN412272) SB-431542