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  • 产品名称：PD173074

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  • 产品厂商：Biovision
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简单介绍：
PD173074
详情介绍：
Characteristics A potent and selective FGFR1 tyrosine kinase inhibitor (IC50 = 21.5 nM). Blocking of the FGFR signaling pathway by PD 173074 leads to self-renewal of stem cells via ERK1/2 activation. Treatment of FGF2-expressing human multipotent adipose-derived stem cells with PD173074 decreases dramatically their clonogenicity and differentiation potential.
Purity ≥ 98 % by TLC
Chemical Name N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea
Formula C₂₈H₄₁N₇O₃
Permeability Cell-permeable
Molecular Weight 523.67 g/mol
CAS-No 219580-11-7
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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image for PD 173074 (ABIN412273) PD 173074