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  • 产品名称:CompoundE

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CompoundE
详情介绍:
Characteristics A potent, selective, non-transition state and non-competitive inhibitor of gamma-secretase (IC50 = 0.3 nM for total beta-amyloid) and Notch processing. At higher concentrations (20-400 µM), only weakly affects the presenilase activity.
Purity ≥ 98 % by HPLC
Chemical Name (2S)-2-([(3,5-Difluorophenyl)acetyl]amino)-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide
Formula C₂₇H₂₄F₂N₄O₃
Permeability Cell-permeable
Molecular Weight 490.5 g/mol
CAS-No 209986-17-4
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 36 months
Supplier Images
 image for Compound E (ABIN629365) Compound E