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  • 产品名称：RITA

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  • 产品厂商：Biovision
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简单介绍：
RITA
详情介绍：
Purpose RITA (reactivation of p53 and induction of tumor cell apoptosis) binds to p53 and induces its accumulation in tumor cells.
Characteristics Off-white solid
Molecular formular: C14H12O3S2
Purity ≥ 98 % by HPLC
Chemical Name 5,5'-(2,5-Furandiyl)bis-2-thiophenem​ethanol; NSC 652287
Formula C₁₄H₁₂O₃S₂
Permeability Cell-permeable
Molecular Weight 292.37 g/mol
CAS-No 213261-59-7
Comment

Synonyms:
5,5'-(2,5-Furandiyl)bis-2-thiophenemethanol, NSC 652287
RITA (reactivation of p53 and induction of tumor cell apoptosis) binds to p53 and induces its accumulation in tumor cells. RITA prevents p53-HDM2 interaction in vitro and in vivo and affects p53 interaction with several negative regulators. It induces expression of p53 target genes and apoptosis in various tumor cell lines expressing wild-type p53
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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