产品详情
所在位置: 首页> 产品目录> 辅助试剂>
查看大图

  • 产品名称：WZ4002

  • 产品型号：
  • 产品厂商：Biovision
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
WZ4002
详情介绍：
Purpose A third generation EGFR inhibitor.
Characteristics Pale yellow solid
Molecular formular: C25H27ClN6O3
Purity ≥ 98 % by HPLC
Chemical Name N-(3-(5-chloro-2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-yloxy)phenyl)acrylamide
Formula C₂₅H₂₇ClN₆O₃
Permeability Cell-permeable
Molecular Weight 494.97 g/mol
CAS-No 1213269-23-8
Comment

Synonyms:
N-(3-(5-chloro-2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-yloxy)phenyl)acrylamide
A third generation EGFR inhibitor. Selectively inhibits mutant EGFR T790M. Inhibits EGFR phosphorylation and induces siginificant tumor regressionin murine model of EGFR T790M. WZ4002 can overcome anoikis resistance in EGFR-mutant lung adenocarcinomas more effectively than Src inhibitors
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for WZ4002 (ABIN1889018) WZ4002