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Purpose
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A deubiquitinylating enzymes (DUB) inhibitor
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Characteristics
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A cell-permeable, reversible, and broad-spectrum inhibitor of the deubiquitinylating enzymes (DUBs). Treatment of cells with PR-619 results in the accumulation of both ubiquitin and sumo-conjugated proteins.
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Purity
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≥ 98 % by HPLC
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Chemical Name
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2,6-Diaminopyridine-3,5-bis(thiocyanate), 3,5-Dithiocyanatopyridine-2,6-diamine
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Formula
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C₇H₅N₅S₂
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Permeability
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Cell-permeable
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Solubility
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DMSO (approx. 5 mg/mL)
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