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Comment
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Synonyms:
(3S,4R,4aR,6S,6aS,7S,8R,8aS,8bR,9S,9aS)-dodecahydro-4,6,7,8a,8b,9a-hexahydroxy-3,6a,9-trimethyl-7-(1-methylethyl)-6,9-methanobenzo[1,2]pentaleno[1,6-bc]furan-8-yl ester-1H-pyrrole-2-carboxylic acid
Ryanodine is a naturally occurring poisonous alkaloid that acts as a potent inhibitor of Ca2+ release from sarcoplasmic reticulum (ICs = 10 and 2.8 nM in skeletal and cardiac muscle, respectively). At micromolar (approx. 100 M) concentrations, ryanodine irreversibly inhibits ryanodine receptor channel opening, which results in paralysis
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