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  • 产品名称：BCl-2InhibitorGX15-070

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  • 产品厂商：Biovision
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简单介绍：
BCl-2InhibitorGX15-070
详情介绍：
Purpose A Bcl-2 inhibitor
Characteristics A small molecule pan-Bcl-2 antagonist that mimics BH3-only proteins by binding to multiple antiapoptotic Bcl-2 members. GX15-070 has been shown to overcome Bcl-2-, Bcl-xl-, Bcl-w-, and Mcl-1-mediated resistance to Bax or Bak. It potently interferes with the direct interaction between Mcl-1 and Bak in intact outer mitochondrial membrane and inhibits the association between Mcl-1 and Bak in intact cells.
Purity ≥ 98 %
Chemical Name (Z)-2-(2-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-3-methoxy-2H-pyrrol-5-yl)-1H-indole methanesulfonate
Formula C₂₀H₁₉N₃O
Permeability Cell-permeable
Solubility DMSO (>80 mg/ml)
Molecular Weight 317.38 g/mol
CAS-No 803712-79-0
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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