产品详情
所在位置: 首页> 产品目录> 辅助试剂>
查看大图

  • 产品名称：KN-93

  • 产品型号：
  • 产品厂商：Biovision
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
KN-93
详情介绍：
Purpose A potent inhibitor of Ca2+/calmodulin-dependent kinase type II
Characteristics White solid
Molecular formular: C26H29ClN2O4S
Purity ≥ 98 %
Chemical Name N-​[2-​[[[3-​(4-​chlorophenyl)-​2-​propen-​1-​yl]methylamino]methyl]phenyl]-​N-​(2-​hydroxyethyl)-​4-​methoxy-​benzenesulfonamide
Formula C₂₆H₂₉ClN₂O₄S
Permeability Cell-permeable
Molecular Weight 501.04 g/mol
CAS-No 139298-40-1
Comment

Synonyms:
KN-93
Cell-permeable.
KN-93 is a potent inhibitor of Ca2+/calmodulin-dependent kinase type II (CaM kinase II) (IC = 0.37 M). It does not affect the activities of PKA, PKC, MLCK, or Ca2+-phosphodiesterase. Also a direct extracellular open channel blocker of voltage-gated potassium channels (IC = 307 nM for Kv1.5). More recently, KN-93 has been used to implicate roles for CaMKII in Ca2+-induced Ca2+ release in cardiac myocytes
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for KN-93 (ABIN1889071) KN-93