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  • 产品名称：SIRT2Inhibitor,B2

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  • 产品厂商：Biovision
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简单介绍：
SIRT2Inhibitor,B2
详情介绍：
Purpose A potent SIRT2 inhibitor
Characteristics Cell-permeable. A Sirtuin 2 (SIRT2) inhibitor (IC50 = 35 µM). Promotes inclusion formation in cellular models of both Huntington,'s disease and Parkinson,'s disease. Prevents huntingtin-mediated proteasome dysfunction and reduces alpha-synuclein-mediated toxicity.
Synonyms: 5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline, CPNQ
Purity ≥ 95 %
Chemical Name 5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline, CPNQ
Formula C₂₀H₁₇ClN₄O₃
Permeability Cell-permeable
Solubility DMSO (>5 mg/mL)
Molecular Weight 396.83 g/mol
CAS-No 115687-05-3
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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