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  • 产品名称：Jervine

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  • 产品厂商：Biovision
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简单介绍：
Jervine
详情介绍：
Purpose Inhibits the sonic hedgehog (shh) pathway by interacting with smoothened.
Characteristics White to off-white solid
Molecular formular: C27H39NO3
Purity ≥ 98 % by TLC
Chemical Name (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,1-1bR)-2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexad-ecahydro-3-hydroxy-3',6',10,11b-tetramethyl-Spiro[9H--benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1-H)-one
Formula C₂₇H₃₉NO₃
Permeability Cell-permeable
Molecular Weight 425.6 g/mol
CAS-No 469-59-0
Comment

Synonyms:
(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS)-2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one
Cell-permeable.
Structurally similar to cyclopamine. Inhibits the sonic hedgehog (shh) pathway by interacting with smoothened. Jervine can be used to induce abnormal morphogenesis in a number of experimental models. Tomatidine is a useful negative control
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 36 months
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