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  • 产品名称：DPPIVInhibitor,NVPDPP728

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  • 产品厂商：Biovision
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简单介绍：
DPPIVInhibitor,NVPDPP728
详情介绍：
Purpose A potent DPP IV Inhibitor
Characteristics A potent, selective, reversible, and slow binding dipeptidyl peptidase IV inhibitor (IC₅₀ = 14 nM). Displays >15,000 fold selectivity over DPP-II and a range of Proline-cleaving proteases. Displays anti-diabetic activity in vivo, improves glucose tolerance, increases glucagon-like peptide 1 (GLP-1) and insulin levels, and augments insulin secretion and GLUT-2 levels.
Purity ≥ 98 % by HPLC
Chemical Name 6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitrile Dihydrochloride
Formula C₁₅H₁₈N₆O.2HCl
Permeability Cell-permeable
Solubility DMSO (approx. 100 mM) or EtOH (approx. 100 mM)
Molecular Weight 371.27 g/mol
CAS-No 247016-69-9
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 48 months
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