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  • 产品名称：AktInhibitor(10-NCP)

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  • 产品厂商：Biovision
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简单介绍：
AktInhibitor(10-NCP)
详情介绍：
Purpose A reversible and specific inhibitor of Akt activity in vitro 
Characteristics A reversible and specific inhibitor of Akt activity in vitro (complete inhibition at < 5 µM). Displays minimal effect on PI 3-K, PDK1, or SGK1. Blocks IGF-I stimulated nuclear translocation of Akt in Rh1 cells and suppressed growth of Rh1, Rh18, and Rh30 cells (IC50= 2-5 µM). Also shown to induce neuronal autophagy in an Akt- and mTOR-independent manner and enhances the clearance of misfolded protein.
Purity ≥ 98 % by HPLC
Chemical Name 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine hydrochloride
Formula C₂₀H₂₅ClN₂O∙HCl
Permeability Cell-permeable
Solubility DMSO (60 mg/ml) or H2O (1 mg/ml)
Molecular Weight 381.34 g/mol
CAS-No 925681-41-0
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 36 months
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image for Akt Inhibitor (10-NCP) (ABIN1685699) Akt Inhibitor (10-NCP)