| Purpose | A TGF-β type I receptor (ALK5) inhibitor | 
                                                                                                                                                                
                                                                                    | Brand | EZSolution™ | 
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
                                                                                    | Characteristics | A 10 mM (5 mg in 1740 µl) of the ALK5 inhibitor RepSox (ABIN629269) in anhydrous DMSO. Synonyms: E-616452
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                                                                                    | Purity | ≥ 98 % by HPLC | 
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
                                                                                    | Chemical Name | 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine; E-616452 | 
                                                                                                                                                                
                                                                                    | Formula | C₁₇H₁₃N₅ | 
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
                                                                                    | Permeability | Cell-permeable | 
                                                                                                                                                                                                                                                            
                                                                                    | Solubility | DMSO |