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  • 产品名称:DUBInhibitor,NSC-632839

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简单介绍:
DUBInhibitor,NSC-632839
详情介绍:
Purpose A pan-specific ubiquitin isopeptidase inhibitor
Characteristics PubChem CID: 5351362
A pan-specific ubiquitin isopeptidase inhibitor (IC₅₀ = 45, 37 and 9.8 µM for USP2, USP7 and SENP2 respectively). NSC-632839 does not affect proteasome proteolytic activity. Induces apoptosis via a Bcl-2-dependent but apoptosome-independent mitochondrial pathway.
Purity ≥ 98 % by HPLC
Chemical Name 3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride
Formula C₂₁H₂₁NO • HCl
Permeability Cell-permeable
Solubility DMSO (~8 mg/ml)
Molecular Weight 339.86 g/mol
CAS-No 157654-67-6
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
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