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  • 产品名称：Semagacestat

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  • 产品厂商：Biovision
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简单介绍：
Semagacestat
详情介绍：
Purpose A potent -secretase inhibitor
Characteristics White solid
Molecular formular: C19H27N3O4
Purity ≥ 98 % by HPLC
Chemical Name (S)-2-hydroxy-3-methyl-N-((S)-1-((S)-3-methyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-ylamino)-1-oxopropan-2-yl)butanamide ; LY450139
Formula C₁₉H₂₇N₃O₄
Permeability Cell-permeable
Molecular Weight 361.44 g/mol
CAS-No 425386-60-3
Comment

Synonyms:
(S)-2-hydroxy-3-methyl-N-((S)-1-((S)-3-methyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-ylamino)-1-oxopropan-2-yl)butanamide , LY450139
A potent -secretase inhibitor (IC = 10.9 nM, 12.1 nM and 12.0 nM for A42, A40 and A38, respectively). Semagacestat has shown to reduce the rate of formation of amyloid- in vitro and in vivo
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 36 months
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