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  • 产品名称:SykInhibitor

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简单介绍:
SykInhibitor
详情介绍:
Purpose A potent and reversible Syk inhibitor
Characteristics An oxindole derivative that acts as a potent, reversible, and ATP-competitive Spleen tyrosine kinase (Syk) inhibitor (IC50 = 14 nM). Has been shown to effectively inhibit FcepsilonRI-mediated degranulation in the rat basophilic leukemia cell line, RBL-2H3 (EC50 = 313 nM).
Purity ≥ 97 % by HPLC (sum of two isomers)
Chemical Name Spleen Tyrosine Kinase Inhibitor
Formula C₁₈H₁₅N₃O₃S
Permeability Cell-permeable
Solubility DMSO
Molecular Weight 353.39 g/mol
CAS-No 622387-85-3
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and mositure
Storage -20 °C
Expiry Date 60 months
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