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  • 产品名称：Daminozide

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  • 产品厂商：Biovision
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简单介绍：
Daminozide
详情介绍：
Purpose A highly selective inhibitor of the human 2-oxoglutarate (JmjC) histone demethylases KDM2A, PHF8, and KDM7A
Characteristics White solid
Molecular formular: C6H12N2O3
Purity ≥ 95 %
Chemical Name 1-​(2,​2-​dimethylhydrazide)-​butanedioic acid; Succinic acid mono(2,2-dimethylhydrazide)
Formula C₆H₁₂N₂O₃
Permeability Cell-permeable
Molecular Weight 160.17 g/mol
CAS-No 1596-84-5
Comment

Synonyms:
1-(2,2-dimethylhydrazide)-butanedioic acid, Succinic acid mono(2,2-dimethylhydrazide)
A highly selective inhibitor of the human 2-oxoglutarate (JmjC) histone demethylases KDM2A, PHF8, and KDM7A with IC values of 1.5, 0.55, and 2.1 M, respectively. When tested for inhibition of other demethylase subfamily members (KDM3, KDM4, KDM5, KDM6) and other 2OG oxygenases (FIH, PHD2, BBOX1), daminozide was considerably less potent (IC's > 100 M)
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for Daminozide (ABIN1889087) Daminozide