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  • 产品名称：EZSolution™Stat3InhibitorI,S3I-201

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  • 产品厂商：Biovision
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简单介绍：
EZSolution™Stat3InhibitorI,S3I-201
详情介绍：
Purpose Stat3 Inhibitor I
Brand EZSolution™
Characteristics Inhibits Stat3.Stat3 complex formation and Stat3-DNA binding activity in vitro (IC₅₀ = 86 ± 33 µM) and Stat3-dependent transcriptional activities. S3I-201 inhibits the expression of the Stat3-regulated genes encoding cyclin D1, Bcl-xL, and survivin and inhibits the growth of human breast tumors in vivo.
Purity ≥ 97 % by HPLC
Chemical Name 2-Hydroxy-4-[[[[4-methylphenyl)sulfonyl]oxy]acetyl]amino]-benzoic acid; NSC 74859; S3I-201
Formula C₁₆H₁₅NO₇S
Permeability Cell-permeable
Solubility DMSO
Molecular Weight 365.36 g/mol
CAS-No 501919-59-1
Comment

Inhibits Stat3.Stat3 complex formation and Stat3-DNA binding activity in vitro (IC = 86 ± 33 µM) and Stat3-dependent transcriptional activities. S3I-201 inhibits the expression of the Stat3-regulated genes encoding cyclin D1, Bcl-xL, and survivin and inhibits the growth of human breast tumors in vivo
Restrictions For Research Use only
Format Liquid
Concentration 10 mM
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 12 months
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