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  • 产品名称:EZSolution™Nec-1s

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  • 产品厂商:Biovision
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简单介绍:
EZSolution™Nec-1s
详情介绍:
Purpose A potent necroptosis inhibitor.
Brand EZSolution™
Characteristics Molecular formular: C13H12ClN3O2
Purity ≥ 96 % by LC-MS
Chemical Name 5-((7-Cl-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione); 7-Cl-O-Nec-1
Formula C₁₃H₁₂ClN₃O₂
Permeability Cell-permeable
Molecular Weight 277.71 g/mol
Comment

Synonyms:
5-((7-Cl-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione), 7-Cl-O-Nec-1
A potent necroptosis inhibitor. Displays higher activity in inhibiting necroptosis in Jurkat cells than Nec-1 (Cat. No. 1864) (EC = 210 nM versus EC = 490 nM), as well as showing no nonspecific cytotoxicity at high concentrations (approx. 100 mM). More useful for in-cell and in vivo experiments compared to Nec-1

Restrictions For Research Use only
Format Liquid
Concentration 10 mM
Buffer anhydrous DMSO
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 12 months
Supplier Images
 image for EZSolution™ Nec-1s (ABIN1888962) EZSolution™ Nec-1s