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  • 产品名称:CalpainInhibitorII,ALLM

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  • 产品厂商:Biovision
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简单介绍:
CalpainInhibitorII,ALLM
详情介绍:
Purpose A Calpain inhibitor
Sequence N-Acetyl-Leu-Leu-Methional
Characteristics A cell-permeable inhibitor of calpain 1 (Ki = 120 nM) and calpain 2 (Ki = 230 nM). Also potently inhibits cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 0.6 nM). Shown to induce caspase-dependent apoptosis in human acute lymphoblastic leukemia and non-Hodgkin,'s Lymphoma cells.
Purity ≥ 95 % by HPLC
Chemical Name Ac-LLM-CHO, N-Acetyl-Leu-Leu-Methional
Formula C₁₉H₃₅N₃O₄S
Permeability Cell-permeable
Solubility DMSO (25 mg/ml) or EtOH (25 mg/ml)
Molecular Weight 401.57 g/mol
CAS-No 136632-32-1
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Powder
Handling Advice Protect from moisture and air
Storage -20 °C
Expiry Date 24 months
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