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  • 产品名称：AG1478

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  • 产品厂商：Biovision
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简单介绍：
AG1478
详情介绍：
Characteristics Cell-permeable. A potent EGFR Tyrosine Kinase (TK) inhibitor with an IC50 of 3 nM. Only weakly inhibits PDGFR and HER2-NEU kinases (IC50 >100 µM).
Purity ≥ 98 % by HPLC
Chemical Name 4-(3'-Chloroanilino)-6,7-dimethoxyquinazoline; Tyrphostin AG 1478
Formula C₁₆H₁₄ClN₃O₂
Permeability Cell-permeable
Molecular Weight 315.75 g/mol
CAS-No 175178-82-2
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 48 months
Supplier Images
image for AG 1478 (ABIN629101) AG 1478
Product cited in: Ito, Correll, Schiel, Finigan, Prekeris, Mason: "Lung fibroblasts accelerate wound closure in human alveolar epithelial cells through hepatocyte growth factor/c-Met signaling." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 307, Issue 1, pp. L94-105, 2014 (PubMed).