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  • 产品名称：BEZ235(NVP-BEZ235)

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  • 产品厂商：Biovision
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简单介绍：
BEZ235(NVP-BEZ235)
详情介绍：
Characteristics Orally active PI-3 kinase inhibitor, Dual PI3K/mTOR inhibition, BEZ235 showed high target specificity and demonstrated anti-proliferative activity against tumor cell lines in animal models of cancer.
Purity ≥ 99 % by HPLC
Chemical Name NVP-BEZ235
Formula C₃₀H₂₃N₅O
Permeability Cell-permeable
Molecular Weight 469.55 g/mol
CAS-No 915019-65-7
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
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image for BEZ235 (NVP-BEZ235) (ABIN412233) BEZ235 (NVP-BEZ235)
Product cited in: Berdichevsky, Dryer, Saponjian, Mahoney, Pimentel, Lucini, Usenovic, Staley: "PI3K-Akt signaling activates mTOR-mediated epileptogenesis in organotypic hippocampal culture model of post-traumatic epilepsy." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 21, pp. 9056-67, 2013 (PubMed).