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  • 产品名称：Okadaicacid

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  • 产品厂商：Biovision
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简单介绍：
Okadaicacid
详情介绍：
Characteristics A Potent inhibitor of protein phosphatases 1 and 2A in numerous cell types. Does not affect activity of acid phosphatase, alkaline phosphatase and tyrosine phosphatase. Non-phorbol type tumor promoter. Induces apoptosis in human breast carcinoma cells (MB-231 and MCF-7) and in myeloid cells, but inhibits glucocorticoid-induced apoptosis in T-cell hybridomas.
Purity > 98 %
Chemical Name OA
Formula C₄₄H₆₈O₁₃
Permeability Cell-permeable
Molecular Weight 805 g/mol
CAS-No 78111-17-8
Restrictions For Research Use only
Format Solid
Handling Advice Protect from moisture. Tumor promoter
Storage -20 °C
Expiry Date 12 months
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image for Okadaic acid (ABIN1889080) Okadaic acid
Product cited in: Huang, Lin, Chang, Lu, Hsu, Wong, Wang: "Human JC virus small tumour antigen inhibits nucleotide excision repair and sensitises cells to DNA-damaging agents." in: Mutagenesis, Vol. 30, Issue 4, pp. 475-85, 2015 (PubMed).