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  • 产品名称：Bosutinib(SKI-606)

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  • 产品厂商：Biovision
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Bosutinib(SKI-606)
详情介绍：
Characteristics Bosutinib (SKI-606) is a novel tyrosine kinase inhibitor. Bosutinib can overcome not only Bcr-Abl-dependent mechanisms of resistance, but also those that are Bcr-Abl-independent.It is used to treat patients with chronic myelogenous leukemia (CML) who demonstrate resistance to Imatinib or develop resistance during treatment.
Purity ≥ 99 % by HPLC
Chemical Name SKI-606
Formula C₂₆H₂₉Cl₂N₅O₃
Permeability Cell-permeable
Molecular Weight 530.45 g/mol
CAS-No 380843-75-4
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 24 months
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image for Bosutinib (SKI-606) (ABIN412165) Bosutinib (SKI-606)
Product cited in: Lee, Jeng, Chen, Chung, Yuan: "Gas6/Axl pathway promotes tumor invasion through the transcriptional activation of Slug in hepatocellular carcinoma." in: Carcinogenesis, Vol. 35, Issue 4, pp. 769-75, 2014 (PubMed).