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  • 产品名称：Rapamycin

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  • 产品厂商：Biovision
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简单介绍：
Rapamycin
详情介绍：
Characteristics An immunosuppressant. Selectively blocks signaling that leads to p70 S6 kinase activation (IC50 = 50 pM). Inhibits lymphokine-induced cell proliferation at the G1 phase. Induces apoptosis in a murine B cell line. Rapamycin has been used in vivo studies by i.p., i.m., and i.v. administrations.
Purity ≥ 99 %
Chemical Name 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine, AY 22989, Sirolimus
Formula C₅₁H₇₉NO₁₃
Permeability Cell-permeable
Molecular Weight 914.19 g/mol
CAS-No 53123-88-9
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 24 months
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image for Rapamycin (ABIN412140) Rapamycin
Product cited in: Totary-Jain, Sanoudou, Dautriche, Schneller, Zambrana, Marks: "Rapamycin resistance is linked to defective regulation of Skp2." in: Cancer research, Vol. 72, Issue 7, pp. 1836-43, 2012 (PubMed).