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  • 产品名称:U0126

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  • 产品厂商:Biovision
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U0126
详情介绍:
Characteristics Potent and selective non-competitive inhibitor of MAP kinase kinase(MEK). Inhibits MEK-1 and MEK-2 (IC50 values of 0.07 and 0.06 µM respectively) with little or no effect on the activities of PKC, Abl, Raf, MEKK, ERK, JNK, MKK-3, MKK-4/SEK, MKK-6, Cdk2 or Cdk4.
Purity ≥ 98 % by HPLC
Chemical Name 1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene
Formula C₁₈H₁₆N₆S₂
Permeability Cell-permeable
Molecular Weight 380.48 g/mol
CAS-No 109511-58-2
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
Supplier Images
 image for U0126 (ABIN412266) U0126
Product cited in: Lee, Lee, Kim, Kim: "Arabidopsis putative MAP kinase kinase kinases Raf10 and Raf11 are positive regulators of seed dormancy and ABA response." in: Plant & cell physiology, Vol. 56, Issue 1, pp. 84-97, 2015 (PubMed).