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  • 产品名称：Pifithrin-ɑ

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  • 产品厂商：Biovision
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Pifithrin-ɑ
详情介绍：
Characteristics A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Reversibly blocks p53-dependent transcriptional activation and apoptosis.
Purity ≥ 99 %
Chemical Name PFT-α, 2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone hydrobromide
Formula C₁₆H₁₈N₂OS . HBr
Permeability Cell-permeable
Molecular Weight 367.3 g/mol
CAS-No 63208-82-2
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 24 months
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image for Pifithrin-ɑ (ABIN412121) Pifithrin-ɑ
Product cited in: Zhang, Xing, Liu: "PUMA promotes Bax translocation by both directly interacting with Bax and by competitive binding to Bcl-X L during UV-induced apoptosis." in: Molecular biology of the cell, Vol. 20, Issue 13, pp. 3077-87, 2009 (PubMed).