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  • 产品名称：PD98059

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  • 产品厂商：Biovision
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简单介绍：
PD98059
详情介绍：
Characteristics A potent, selective and cell-permeable inhibitor of MAP kinase kinase (MEK). It inhibits phosphorylation of MAP kinase by MEK. PD 98059 does not inhibit MAP kinase itself.
Purity ≥ 98 % by HPLC
Chemical Name 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one
Formula C₁₆H₁₃NO₃
Permeability Cell-permeable
Molecular Weight 267.28 g/mol
CAS-No 167869-21-8
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for PD 98059 (ABIN412263) PD 98059
Product cited in: Noda, Matsumoto, Fukuyama, Asai, Kitajima, Seki, Matsunaga, Kan-O, Moriwaki, Morimoto, Inoue, Nakanishi: "Cigarette smoke impairs phagocytosis of apoptotic neutrophils by alveolar macrophages via inhibition of the histone deacetylase/Rac/CD9 pathways." in: International immunology, Vol. 25, Issue 11, pp. 643-50, 2013 (PubMed).