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  • 产品名称：CAMPResponsiveElementBindingProtein1(CREB1)Peptide

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  • 产品厂商：Biovision
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简单介绍：
CAMPResponsiveElementBindingProtein1(CREB1)Peptide
详情介绍：
Purpose Blocking Peptide for CREB polyclonal antibody (3360R-100).
Blocked Antibody anti-CREB1 antibody (CAMP Responsive Element Binding Protein 1) (ABIN411455)
Characteristics Blocking Peptide for CREB polyclonal antibody .
Country of Manufacture: USA
Background Transcription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors. Protein kinase A and the calmodulin-dependent protein kinase CaMKII stimulate CREB phosphorylation at Ser133, a key regulatory site controlling transcriptional activity. Phosphorylation at Ser133 is also mediated by p44/42 MAP kinase, p90RSK, p38 MAP kinase and MSK1. CREB appears to play an important role in learning and memory in both flies and mice.
Gene ID 81646
Research Area Immunology, Innate Immunity, Transcription Factors
Application Notes Transcription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors. Protein kinase A and the calmodulin-dependent protein kinase CaMKII stimulate CREB phosphorylation at Ser133, a key regulatory site controlling transcriptional activity. Phosphorylation at Ser133 is also mediated by p44/42 MAP kinase, p90RSK, p38 MAP kinase and MSK1. CREB appears to play an important role in learning and memory in both flies and mice.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer 50 μg (0.5 mg/mL) in phosphate buffered saline (PBS), pH 7.2, containing 50 % glycerol, 1 % BSA and 0.02 % thimerosal.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The peptide solution should be gently mixed before use.
Storage -20 °C
Expiry Date 12 months