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  • 产品名称：µ-ConotoxinPIIIA

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  • 产品厂商：Smartox-Biotech
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简单介绍：
µ-ConotoxinPIIIA
详情介绍：
Purpose µ-Conotoxin PIIIA blocks Nav1.2 and Nav1.7 channels
Sequence H-pGlu-Arg-Leu-Cys4-Cys5-Gly-Phe-Hyp-Lys-Ser-Cys11-Arg-Ser-Arg-Gln-Cys16-Lys-Hyp-His-Arg-Cys21-Cys22-NH2(Disulfide bonds between Cys4-Cys16, Cys5-Cys21 and Cys11-Cys22)
Background µ-Conotoxin PIIIA has been isolated from the venom of the cone Conus purpurascens. µ-Conotoxins bind and block site 1 of voltage-gated sodium channels. This toxin blocks the neuronal sodium channels Nav1.2 (SCN2A) and Nav1.7 (SCN9A). The peptide causes flaccid paralysis in both mice and fish.
Molecular Weight 2604.1 Da
Restrictions For Research Use only