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  • 产品名称：Iberiotoxin(IbTx)

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  • 产品厂商：Smartox-Biotech
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简单介绍：
Iberiotoxin(IbTx)
详情介绍：
Purpose Iberiotoxin (IbTx) is a Kca channel inhibitor
Sequence pGlu-Phe-Thr-AspVal-Asp-Cys-Ser-Val-Ser-Lys-GIu-Cys-Trp-Ser-Val-Cys-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys-Met-Gly-Lys-Lys-Cys-Arg-Cys-Tyr-GIn-OHDisulfid e bridges: Cys7-Cys28, Cys13-Cys33, Cys17-Cys35
Background Iberiotoxin (IbTx) is a toxin that was originally isolated from Buthus tamulus scorpion venom. Iberiotoxin inhibits selectively the high conductance Ca2+-activated K+ channel (KCa1.1). This toxin does not affect other types of voltage-dependent K+ channels which are sensitive to the Charybdotoxin. Iberiotoxin is a valuable tool to study specifically Maxi-K channels.
Molecular Weight 4230.8 Da
CAS-No 129203-60-7
Restrictions For Research Use only