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  • 产品名称:Lipocalin2(LCN2) ELISA Kit

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  • 产品厂商:BioPorto
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简单介绍:
Lipocalin2(LCN2) ELISA Kit
详情介绍:
Purpose A quantitative assay for  the in vitro determination of monkey NGAL in urine, plasma, serum, tissue extracts or culture media.
Sample Type Urine, Plasma, Serum, Tissue Culture Supernatant
Analytical Method Quantitative
Detection Method Colorimetric
Specificity The Monkey NGAL ELISA Kit allows for the determination of rises in monkey NGAL concentrations. It is to be hoped that the determination of NGAL may become a convenient end-point in Rhesus and Cynomolgus monkey models of renal injury, nephrotoxicity and other nephropathies. With the launch of the Monkey NGAL ELISA Kit, the BioPorto research portfolio offers NGAL measurements for all animals most commonly used in drug development, safety and efficacy profiling.
Sensitivity 1.5 pg/mL
Components 1: 12 strips of 8 Microwells each coated with anti-monkey NGAL (96 wells) + frame
2:5X Sample Diluent
3: 3X Monkey NGAL Calibrator stock 1000 pg/mL.
4: 25X Wash Solution Concentrate
5: Biotinylated Monkey NGAL Antibody
6: HRP-Streptavidin
7: TMB Substrate
8: Stop Solution
Alternative Name NGAL (LCN2 ELISA Kit Abstract)
Background NGAL determination allows kidney injury to be detected almost as soon as it occurs, and not at the later stage when the consequences of impaired kidney function can be detected by existing routine tests and the damage has been consolidated. The Monkey or non-human primate is an important experimental model for medical research because of its close resemblance to the human physiology. Pre-clinical research in monkeys represents one of the final steps towards an approval that allows pharmaceutical companies to proceed to human clinical trials. NGAL has been identified as one of the leading biomarkers for diagnosing acute kidney injury in humans and is therefore often presented as an excellent candidate for the same use in the preclinical testing industry.
Pathways Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis
Application Notes Sample Dillution Guidline: Dilution 1/250
Comment

Wavelength: 450 nm

Assay Time 4 h
Plate Pre-coated
Restrictions For Research Use only
Storage 4 °C
Expiry Date 6 months