产品详情
查看大图

  • 产品名称：FibroblastGrowthFactor1(Acidic)(FGF1)(Active)Protein

  • 产品型号：
  • 产品厂商：BioAcademia
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
FibroblastGrowthFactor1(Acidic)(FGF1)(Active)Protein
详情介绍：
Characteristics Product: Full length recombinant mature FGF-1 (15.8 kDa, 140 amino acids) expressed in E. coli. Activity: The ED50 as determined by a cell proliferation assay using MTS assay kit (Cell Titer 96, Promega) with Balb/c3T3 cells was < 10 pg/mL, corresponding to a specific activity of < 1 x 108 units/mg.
Purity > 98 % as determined by SDS-PAGE (CBB staining)
Sterility Sterile filtered
Background FGF-1 (acidic FGF) is a member of the fibroblast growth factor (FGF) family, which binds heparin. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.
Gene ID 2246
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes 1. Use as a supplement in serum-free or reduced serum media for culture of mammalian cells
2. Studies of the human FGF-1 receptor, transmembrane signaling and protein phosphorylation
3. Western blotting control for anti-EGF-1 antibodies
4. Widely used in cosmetics,such as whitening,anti-wrinkle,anti-aging,etc.
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS (10 mM Na-phosphate, 150 mM NaCl) pH 7.2, 50 % glycerol
Storage -20 °C/-80 °C
Storage Comment -20 C (For long term storage: -70 C)
Product cited in: Zakrzewska, Marcinkowska, Wiedlocha: "FGF-1: from biology through engineering to potential medical applications." in: Critical reviews in clinical laboratory sciences, Vol. 45, Issue 1, pp. 91-135, 2008 (PubMed).