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  • 产品名称:anti-Gal11p(AA1-300),(N-Term)antibody

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  • 产品厂商:BioAcademia
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简单介绍:
anti-Gal11p(AA1-300),(N-Term)antibody
详情介绍:
Immunogen Recombinant N terminal domain (1-300aa) of yeast Gal11p protein expressed in E. coli.
Characteristics Whole Antiserum
Purification Rabbit serum
Background Mediator is a protein complex which performs a very important role both in the transcription at the basal level which does not rely on transcription control factor, and in the transcription activating reaction that relies on the transcription control factor. It has the characteristic of binding to the 7 amino acid repeated structure (CTD) that exists in the C terminal of the biggest subunit of RNA polymerase II. 30 kinds of subunits have already being identified as its composing substances, but it is said that multiple kinds of complexes with various subunit compositions exist in the cells. Gal11p is one of the mediator subunits and is composed of 1081 amino acid residues (120 kDa) .
UniProt P19659
Application Notes Not tested with other applications
Restrictions For Research Use only
Format Liquid
Buffer 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Upon arrival briefly centrifuge down, aliquot and store at -20 C.
Product cited in: Mizuno, Harashima: "Gal11 is a general activator of basal transcription, whose activity is regulated by the general repressor Sin4 in yeast." in: Molecular genetics and genomics : MGG, Vol. 269, Issue 1, pp. 68-77, 2003 (PubMed).

Han, Lee, Kang, Kim: "Med9/Cse2 and Gal11 modules are required for transcriptional repression of distinct group of genes." in: The Journal of biological chemistry, Vol. 276, Issue 40, pp. 37020-6, 2001 (PubMed).