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  • 产品名称：CD177(human):293TLysate

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  • 产品厂商：BioLeaf
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CD177(human):293TLysate
详情介绍：
Characteristics CD177 is an important neutrophil gene that encodes the neutrophil membrane glycoprotein (gp) NB1. NB1 gp has been studied for more than 20 years and during that time several different names have been used to describe this gp, its antigens, and the gene that encodes this molecule. NB1 was first described by Lalezari and colleagues while investigating a case of neonatal alloimmune neutropenia. Occasionally, during pregnancy, a mother produces alloantibodies to neutrophil antigens than cross the placenta, react with neutrophils in the fetus, and cause the neonate to become neutropenic. One antigen recognized by such antibodies was described as \\
Alternative Name CD177
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes CD177 (h): 293T Lysate is suitable as a Western Blotting positive control for human reactive CD177 antibodies. Recommended use: 10-20 µl per lane. Control 293T Lysate: 293LYS is available as a Western Blotting negative control lysate derived from non-transfected 293T cells.
Restrictions For Research Use only
Handling Advice Repeated freezing and thawing should be minimized. Sample vial should be boiled once prior to use. Non-hazardous. No MSDS required.
Storage -20 °C
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image for CD177 (human): 293T Lysate (ABIN1112256) CD177 (human): 293T Lysate
image for CD177 (human): 293T Lysate (ABIN1112256) CD177 (human): 293T Lysate (Image 2)
Product cited in: Edwards, Durant, Jones, Evans, Smith: "Differential expression of HLA class II antigens in fetal human spleen: relationship of HLA-DP, DQ, and DR to immunoglobulin expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 137, Issue 2, pp. 490-7, 1986 (PubMed).

Austin, Trowsdale, Rudd, Bodmer, Feldmann, Lamb: "Functional expression of HLA-DP genes transfected into mouse fibroblasts." in: Nature, Vol. 313, Issue 5997, pp. 61-4, 1985 (PubMed).

Royston, Omary, Trowbridge: "Monoclonal antibodies to a human T-cell antigen and Ia-like antigen in the characterization of lymphoid leukemia." in: Transplantation proceedings, Vol. 13, Issue 1 Pt 2, pp. 761-6, 1981 (PubMed).

Background publications Watson, DeMars, Trowbridge, Bach: "Detection of a novel human class II HLA antigen." in: Nature, Vol. 304, Issue 5924, pp. 358-61, 1983 (PubMed).