|
Background
|
Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence. Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer. Binds DNA in a homo- or heterodimeric form.
Alias Symbols: TCFEC, TFECL, bHLHe34, TFE-C, TFEC-L, hTFEC-L
Protein Interaction Partner: DEFB127, NAPB, ZMAT2, HNRNPA1, DCK, TFEC, TFEB, TFE3, MITF,
|