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Background
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This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.
Alias Symbols: OIP1, OIP-1, ZRP-1, TRIP-6, MGC3837, MGC4423, MGC10556, MGC10558, MGC29959, TRIP6i2
Protein Interaction Partner: FASLG, SLC25A6, ABI2, CREB5, STK16, NCK2, TPM3, TMSB4X, RFX3, RAD23A, PRKAA2, PRKAA1, PIN1, PDGFRB, NEDD9, LMO2, KIR2DL4, HOXB9, HLA-DPB1, GNAI2, CNTF, BYSL, ATP5O, RHOA, AQP1, KRTAP26-1, INCA1, CEP57L1, POM121L4P, RNF214, TTLL10, MSRB3, FAM154A, TEKT4, L
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