产品详情
  • 产品名称:PBEF1ProteinLysate(GSTtagged)(Expressedinbacteria)

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  • 产品厂商:AvivaSysBio
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简单介绍:
PBEF1ProteinLysate(GSTtagged)(Expressedinbacteria)
详情介绍:
Characteristics Partial length PBEF1 is expressed in E. coli.
ProductDetails: Lysate Fraction Whole Cell Lysate
Lysate Type Protein Lysate
Alternative Name NAMPT
Background PBEF1 catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

Alias Symbols: 1110035O14Rik, DKFZp666B131, MGC117256, PBEF, VF, VISFATINi1/4>NAMPT, PBEF1, VISFATIN

Protein Interaction Partner: UBC, NEDD8, NDRG1, CTSA, PEPD, MVD, GSR, ASS1, ANXA6, CD81, AKT2, ADORA2A, IFITM3, ND1, GGT1, FTL, CUL5, DDA1, GBAS, FANCA,
Molecular Weight 48 kDa
Gene ID 10135
NCBI Accession NM_005746, NP_005737
UniProt P43490
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of distilled water. Final concentration is 1 mg/mL.
Concentration 1mg/mL
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.