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Background
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Involved in maintaining the transcriptionally repressive state of genes. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
Alias Symbols: CBX7
Protein Interaction Partner: EED, RNF2, PCGF2, TPR, RING1, RAD17, PHC2, CSNK2B, CSNK2A1, BMI1, CBX7, PCGF3, DCAF7, UBE4A, PCGF1, PCGF5, PCGF6, B3GNT5, CDC42SE1, SRBD1, UCHL5, HMGA1, HDAC2, SUV39H2, HIST3H3, HIST1H4A, HIST1H3A,
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