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Background
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The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals.
Alias Symbols: API1, MIHB, HIAP2, RNF48, cIAP1, Hiap-2, c-IAP1
Protein Interaction Partner: UBC, RAC1, NMB, GFAP, ENDOG, CASP9, PCSK9, PPM1K, TSGA10, GCC1, BIRC7, EXOSC5, DIABLO, EAF2, WDYHV1, MAP3K14, BOLA1, BIRC2, PACS2, MAP3K2, UBE2D1, MAP3K3, CDC42, RHOA, TRAF2, RNF31, TNFAIP3, EGFR, RIPK1, CD40LG, TRIM34, RNF181, IKBKG, WDR82, OTUB1, UBR5,
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