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Background
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The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ET1, PPET1, HDLCQ7
Protein Interaction Partner: EDN1, EDNRA, UBQLN4, COPS6, EDNRB, ECE1, BAG6, MME, CMA1, KEL, ADM,
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