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  • 产品名称：NOX4ProteinLysate(GSTtagged)(Expressedinbacteria)

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  • 产品厂商：AvivaSysBio
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简单介绍：
NOX4ProteinLysate(GSTtagged)(Expressedinbacteria)
详情介绍：
Characteristics Partial length NOX4 is expressed in E. coli.
ProductDetails: Lysate Fraction Whole Cell Lysate
Lysate Type Protein Lysate
Alternative Name NOX4
Background Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 4 displays an increased activity. Isoform 5 and isoform 6 display reduced activity.

Alias Symbols: KOX, KOX-1, RENOX

Protein Interaction Partner: UBC, TLR4,
Molecular Weight 48 kDa
Gene ID 50507
NCBI Accession NM_001143836, NP_058627
UniProt Q9NPH5
Research Area Cardiovascular, Atherosclerosis, Metabolism
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of distilled water. Final concentration is 1 mg/mL.
Concentration 1mg/mL
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.